Dysregulated mesenchymal PDGFR-β drives kidney fibrosis
Kidney fibrosis is characterised by growth and activation of platelet-derived development issue receptor-β (PDGFR-β)-positive mesenchymal cells. To review the implications of PDGFR-β activation, we developed a mannequin of major renal fibrosis utilizing transgenic mice with PDGFR-β activation particularly in renal mesenchymal cells, driving their pathological proliferation and phenotypic change towards myofibroblasts.
This resulted in progressive mesangioproliferative glomerulonephritis, mesangial sclerosis, and interstitial fibrosis with progressive anemia as a consequence of lack of erythropoietin manufacturing by fibroblasts.
Fibrosis induced secondary tubular epithelial harm at later levels, coinciding with microinflammation, and aggravated the development of hypertensive and obstructive nephropathy.
Human Platelet-Derived Growth Factor-BB,PDGF-BB ELISA kit
Inhibition of PDGFR activation reversed fibrosis extra successfully within the tubulointerstitium in comparison with glomeruli. Gene expression signatures in mice with PDGFR-β activation resembled these present in sufferers.
In conclusion, PDGFR-β activation alone is ample to induce progressive renal fibrosis and failure, mimicking key facets of continual kidney illness in people. Our information present direct proof that fibrosis per se can drive continual organ harm and set up a mannequin of major fibrosis permitting particular research focusing on fibrosis development and regression.
AFC1 Compound Attenuated MI/R-Induced Ventricular Transforming through Inhibiting PDGFR and STAT Pathway.
Background: Efficient interventions to enhance the result of sufferers subjected to myocardial ischemia reperfusion (MI/R) are pressing in medical settings. Tanshinone IIA (TSA) is reported to attenuate myocardial harm and enhance ventricular reworking publish MI/R. Right here, we evaluated the efficacy of AFC1 compound that’s much like TSA construction in murine MI/R fashions.
PDGF-BB (P.pastoris-expressed), Human
We discovered that AFC1 had a comparable impact of enhancing murine cardiac perform after MI/R whereas it was superior to TSA in security profile. Administration of AFC1 diminished reactive oxygen species (ROS) manufacturing, inflammatory cells infiltration, and the expression of platelet derived development issue receptors (PDGFR) in infarcted myocardium.
Remedy with AFC1 additionally attenuated MI/R-induced cardiac reworking and contributed to the restoration of cardiac perform. Moreover, AFC1 reversed the elevation of PDGFR expression induced by PDGF-AB in each neonatal rat cardiomyocytes (NCMs) and neonatal rat cardiac fibroblasts (NCFs) and suppressed PDGF-AB induced NCM hypertrophy through STAT3 pathway and NCF collagen synthesis by means of p38-MAPK signaling in vitro. Equally, AFC1 could contribute to the restoration of cardiac perform in mice publish MI/R through suppressing STAT signaling.
Our outcomes confirmed that AFC1 exerts anti-hypertrophic and anti-fibrotic results towards MI/R-induced cardiac reworking, and counsel that AFC1 could have a promising potential in enhancing the result of sufferers who suffered from MI/R.
Human Complement Factor Bb (CFB-Bb) Antibody
 PDGF-BB/ Rat PDGF- BB ELISA Kit |
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| ELA-E0633r | Lifescience Market | 96 Tests | EUR 886 |
 rHu PDGF-BB |
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| AK8292-0002 | Akron Biotech | 2µg | Ask for price |
rHu PDGF-BB |
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| AK8292-0010 | Akron Biotech | 10µg | Ask for price |
rHu PDGF-BB |
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| AK8292-0100 | Akron Biotech | 100µg | Ask for price |
rHu PDGF-BB |
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| AK8292-1000 | Akron Biotech | 1mg | Ask for price |
 anti-PDGF BB |
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| YF-PA13686 | Abfrontier | 50 ug | EUR 363 |
|
Description: Mouse polyclonal to PDGF BB |
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anti-PDGF BB |
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| YF-PA24331 | Abfrontier | 50 ul | EUR 334 |
|
Description: Mouse polyclonal to PDGF BB |
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 PDGF BB protein |
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| 30R-2611 | Fitzgerald | 10 ug | EUR 359 |
|
Description: Purified recombinant Human PDGF BB protein |
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PDGF BB protein |
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| 30R-2612 | Fitzgerald | 10 ug | EUR 302 |
|
Description: Purified recombinant Mouse PDGF BB protein |
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PDGF BB protein |
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| 30R-AP004 | Fitzgerald | 2 ug | EUR 133 |
|
Description: Purified recombinant Human PDGF BB protein |
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PDGF BB protein |
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| 30R-AP051 | Fitzgerald | 10 ug | EUR 273 |
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Description: Purified recombinant Human PDGF BB protein |
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 PDGF-BB, Human |
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| HY-P7055 | MedChemExpress | 10ug | EUR 268 |
 PDGF-BB, Mouse |
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| HY-P7087 | MedChemExpress | 100ug | EUR 946 |
 PDGF-BB, Rat |
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| HY-P7278 | MedChemExpress | 50ug | EUR 383 |
 PDGF-BB, human |
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| RC216-21 | Bio Basic | 2ug | EUR 104.38 |
 PDGF-BB, CF |
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| PR15026CF | Neuromics | 50 ug | EUR 1087 |
PDGF-BB, CF |
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| PR15027CF | Neuromics | 50 ug | EUR 396 |
 Polyclonal PDGF-BB Antibody |
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| APR08990G | Leading Biology | 0.1mg | EUR 484 |
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Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PDGF-BB . This antibody is tested and proven to work in the following applications: |
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Polyclonal PDGF-BB Antibody |
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| APR00412G | Leading Biology | 0.1mg | EUR 484 |
|
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PDGF-BB . This antibody is tested and proven to work in the following applications: |
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 PDGF-BB, human recombinant |
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| 4488-10 | Biovision | EUR 332 | |
PDGF-BB, human recombinant |
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| 4488-1000 | Biovision | EUR 6955 | |
PDGF-BB, human recombinant |
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| 4488-50 | Biovision | EUR 936 | |
 PDGF-BB, murine recombinant |
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| 4489-10 | Biovision | EUR 267 | |
PDGF-BB, murine recombinant |
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| 4489-1000 | Biovision | EUR 5362 | |
PDGF-BB, murine recombinant |
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| 4489-50 | Biovision | EUR 729 | |
 Recombinant Human PDGF-BB |
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| SJA04-01 | Amyotop | 10µg/vial | EUR 256 |
 Human PDGF-BB Protein |
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| abx060208-100ug | Abbexa | 100 ug | EUR 523 |
Human PDGF-BB Protein |
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| abx060258-100ug | Abbexa | 100 ug | EUR 523 |
) rec PDGF BB (human) |
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| H-7530.0002 | Bachem | 2.0µg | EUR 162 |
rec PDGF BB (human) |
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| H-7530.0010 | Bachem | 10.0µg | EUR 381 |
) Polyclonal PDGF-BB Antibody (aa21-70) |
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| APR08991G | Leading Biology | 0.05ml | EUR 484 |
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Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PDGF-BB (aa21-70). This antibody is tested and proven to work in the following applications: |
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) Polyclonal PDGF-BB Antibody (C-Terminus) |
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| APR08992G | Leading Biology | 0.05mg | EUR 484 |
|
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human PDGF-BB (C-Terminus). This antibody is tested and proven to work in the following applications: |
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 PDGF-BB ELISA KIT|Human |
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| EF000205 | Lifescience Market | 96 Tests | EUR 689 |
 (cGMP)) rHu PDGF-BB (yeast) (cGMP) |
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| AK8274-1000 | Akron Biotech | 1mg | Ask for price |
, Human) PDGF-BB (P.pastoris-expressed), Human |
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| HY-P7055A | MedChemExpress | 10ug | EUR 268 |
 Sheep PDGF-BB ELISA Kit |
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| ESP0050 | Abclonal | 96Tests | EUR 521 |
 Rabbit PDGF-BB ELISA Kit |
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| ERTP0634 | Abclonal | 96Tests | EUR 521 |
 Monkey PDGF-BB ELISA Kit |
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| EMKP0050 | Abclonal | 96Tests | EUR 521 |
 Mouse PDGF-BB ELISA Kit |
|||
| EMP0050 | Abclonal | 96Tests | EUR 521 |
Mouse PDGF-BB ELISA Kit |
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| EMP0634 | Abclonal | 96Tests | EUR 521 |
 Porcine PDGF-BB ELISA Kit |
|||
| EPP0050 | Abclonal | 96Tests | EUR 521 |
Porcine PDGF-BB ELISA Kit |
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| EPP0634 | Abclonal | 96Tests | EUR 521 |
 Rat PDGF-BB ELISA Kit |
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| ERP0050 | Abclonal | 96Tests | EUR 521 |
Rat PDGF-BB ELISA Kit |
|||
| ERP0634 | Abclonal | 96Tests | EUR 521 |
Rabbit PDGF-BB ELISA Kit |
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| ERTP0050 | Abclonal | 96Tests | EUR 521 |
 Recombinant Human PDGF-BB Protein |
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| PROTP01127-4 | BosterBio | 10ug | EUR 317 |
|
Description: PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-BB is a 24.3 kDa disulfide-linked homodimer of two B chains (218 total amino acids). |
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 Bovine PDGF-BB ELISA Kit |
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| EBP0634 | Abclonal | 96Tests | EUR 521 |
 Chicken PDGF-BB ELISA Kit |
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| ECKP0050 | Abclonal | 96Tests | EUR 521 |
 Canine PDGF-BB ELISA Kit |
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| ECP0050 | Abclonal | 96Tests | EUR 521 |
Canine PDGF-BB ELISA Kit |
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| ECP0634 | Abclonal | 96Tests | EUR 521 |
 Human PDGF-BB ELISA Kit |
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| EHP0050 | Abclonal | 96Tests | EUR 521 |
Human PDGF-BB ELISA Kit |
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| EHP0634 | Abclonal | 96Tests | EUR 521 |
 Anserini PDGF-BB ELISA Kit |
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| EAP0634 | Abclonal | 96Tests | EUR 521 |
Bovine PDGF-BB ELISA Kit |
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| EBP0050 | Abclonal | 96Tests | EUR 521 |
 Goat PDGF-BB ELISA Kit |
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| EGTP0050 | Abclonal | 96Tests | EUR 521 |
Goat PDGF-BB ELISA Kit |
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| EGTP0634 | Abclonal | 96Tests | EUR 521 |
Human PDGF-BB ELISA Kit |
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| RK04112 | Abclonal | 96 Tests | EUR 521 |
Recombinant Human PDGF-BB Protein |
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| RP00834 | Abclonal | 10 μg | EUR 221 |
 Recombinant Murine PDGF-BB Protein |
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| PROTP31240-1 | BosterBio | 10ug | EUR 317 |
|
Description: PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant murine PDGF-BB is a 24.4 kDa disulfide-linked homodimer of two B chains (218 total amino acids). |
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 PDGF-BB, human recombinant protein |
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| P1047-.01 | ApexBio | 10 µg | EUR 313 |
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Description: The platelet-derived growth factor BB (PDGF-BB) is a member of the PDGF family and is a disulfide-linked homodimer. PDGF family consists of proteins PDGF-A, -B that form three disulfide-linked homodimers (PDGF-AA, -BB and -AB). |
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PDGF-BB, human recombinant protein |
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| P1047-.05 | ApexBio | 50 µg | EUR 877 |
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Description: The platelet-derived growth factor BB (PDGF-BB) is a member of the PDGF family and is a disulfide-linked homodimer. PDGF family consists of proteins PDGF-A, -B that form three disulfide-linked homodimers (PDGF-AA, -BB and -AB). |
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PDGF-BB, human recombinant protein |
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| P1047-1 | ApexBio | 1 mg | EUR 6522 |
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Description: The platelet-derived growth factor BB (PDGF-BB) is a member of the PDGF family and is a disulfide-linked homodimer. PDGF family consists of proteins PDGF-A, -B that form three disulfide-linked homodimers (PDGF-AA, -BB and -AB). |
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 PDGF-BB, murine recombinant protein |
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| P1048-.01 | ApexBio | 10 µg | EUR 313 |
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Description: The platelet-derived growth factor BB (PDGF-BB) is a member of the PDGF family and is a disulfide-linked homodimer. PDGF family consists of proteins PDGF-A, -B that form three disulfide-linked homodimers (PDGF-AA, -BB and -AB). |
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PDGF-BB, murine recombinant protein |
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| P1048-.05 | ApexBio | 50 µg | EUR 877 |
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Description: The platelet-derived growth factor BB (PDGF-BB) is a member of the PDGF family and is a disulfide-linked homodimer. PDGF family consists of proteins PDGF-A, -B that form three disulfide-linked homodimers (PDGF-AA, -BB and -AB). |
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PDGF-BB, murine recombinant protein |
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| P1048-1 | ApexBio | 1 mg | EUR 6522 |
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Description: The platelet-derived growth factor BB (PDGF-BB) is a member of the PDGF family and is a disulfide-linked homodimer. PDGF family consists of proteins PDGF-A, -B that form three disulfide-linked homodimers (PDGF-AA, -BB and -AB). |
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 Recombinant Human Platelet-Derived Growth Factor BB/PDGF-BB |
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| C199-10ug | Novoprotein | 10ug | EUR 202 |
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Description: Lyophilized from a 0.2 μm filtered solution of 4mM HCl. |
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Recombinant Human Platelet-Derived Growth Factor BB/PDGF-BB |
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| C199-1mg | Novoprotein | 1mg | EUR 2283 |
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Description: Lyophilized from a 0.2 μm filtered solution of 4mM HCl. |
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Recombinant Human Platelet-Derived Growth Factor BB/PDGF-BB |
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| C199-500ug | Novoprotein | 500ug | EUR 1613 |
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Description: Lyophilized from a 0.2 μm filtered solution of 4mM HCl. |
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Recombinant Human Platelet-Derived Growth Factor BB/PDGF-BB |
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| C199-50ug | Novoprotein | 50ug | EUR 496 |
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Description: Lyophilized from a 0.2 μm filtered solution of 4mM HCl. |
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 Human CellExp? PDGF-BB, human recombinant |
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| 7276-10 | Biovision | EUR 419 | |
 Human PDGF-BB PicoKine ELISA Kit |
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| EK0956 | BosterBio | 96 wells | EUR 425 |
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Description: For quantitative detection of human PDGF-BB in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). |
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 Guinea Pig PDGF-BB ELISA Kit |
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| EGP0050 | Abclonal | 96Tests | EUR 521 |
Guinea Pig PDGF-BB ELISA Kit |
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| EGP0634 | Abclonal | 96Tests | EUR 521 |
 Rat platelet-derived growth factor-BB,PDGF-BB ELISA Kit |
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| CN-01428R1 | ChemNorm | 96T | EUR 478 |
Rat platelet-derived growth factor-BB,PDGF-BB ELISA Kit |
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| CN-01428R2 | ChemNorm | 48T | EUR 329 |
 Mouse platelet-derived growth factor-BB,PDGF-BB ELISA Kit |
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| CN-02297M1 | ChemNorm | 96T | EUR 492 |
Mouse platelet-derived growth factor-BB,PDGF-BB ELISA Kit |
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| CN-02297M2 | ChemNorm | 48T | EUR 341 |
 Human Platelet-Derived Growth Factor-BB,PDGF-BB ELISA kit |
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| CN-03344H1 | ChemNorm | 96T | EUR 457 |
Human Platelet-Derived Growth Factor-BB,PDGF-BB ELISA kit |
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| CN-03344H2 | ChemNorm | 48T | EUR 306 |
 ELISA kit) Horse platelet-derived growth factor-BB(PDGF-BB) ELISA kit |
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| CSB-EQ027241HO-24T | Cusabio | 1 plate of 24 wells | EUR 165 |
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Description: Quantitativesandwich ELISA kit for measuring Horse platelet-derived growth factor-BB (PDGF-BB) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
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Horse platelet-derived growth factor-BB(PDGF-BB) ELISA kit |
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| 1-CSB-EQ027241HO | Cusabio |
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|
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Description: Quantitativesandwich ELISA kit for measuring Horse platelet-derived growth factor-BB(PDGF-BB) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
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Cadherin-11 binds to PDGFRβ and enhances cell proliferation and tissue regeneration through the PDGFR-AKT signaling axis.
Intercellular adhesion by means of homotypic interplay between cadherins regulates a number of mobile processes together with cytoskeletal group, proliferation, and survival. On this paper, we offer proof that cadherin-11 (CDH11) binds to and promotes cell proliferation each in vitro and in vivo in synergy with the platelet-derived development issue receptor beta (PDGFRβ).
Engagement of CDH11 elevated the sensitivity of cells to PDGF-BB by 10- to 100-fold, leading to fast and sustained phosphorylation of AKT, finally selling and cell proliferation and tissue regeneration.
Certainly, wound therapeutic experiments confirmed that therapeutic was severely compromised in Cdh11-/- mice, as evidenced by considerably decreased proliferation, AKT phosphorylation, and extracellular matrix (ECM) synthesis of dermal cells.
Human Glycogen phosphorylase BB,GP-BB ELISA Kit
Our outcomes shed gentle into understanding how intercellular adhesion can promote cell proliferation and will have implications for tissue regeneration and most cancers development.
anti-PDGF BB |
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| YF-PA13686 | Abfrontier | 50 ug | EUR 363 |
|
Description: Mouse polyclonal to PDGF BB |
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 anti-PDGF AA |
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| YF-PA24330 | Abfrontier | 50 ul | EUR 334 |
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Description: Mouse polyclonal to PDGF AA |
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anti-PDGF BB |
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| YF-PA24331 | Abfrontier | 50 ul | EUR 334 |
|
Description: Mouse polyclonal to PDGF BB |
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 anti-PDGF Receptor alpha |
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| YF-PA13687 | Abfrontier | 50 ug | EUR 363 |
|
Description: Mouse polyclonal to PDGF Receptor alpha |
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anti-PDGF Receptor alpha |
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| YF-PA13688 | Abfrontier | 100 ug | EUR 403 |
|
Description: Rabbit polyclonal to PDGF Receptor alpha |
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 anti-PDGF Receptor beta |
|||
| YF-PA13689 | Abfrontier | 50 ug | EUR 363 |
|
Description: Mouse polyclonal to PDGF Receptor beta |
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anti-PDGF Receptor beta |
|||
| YF-PA13690 | Abfrontier | 100 ug | EUR 403 |
|
Description: Rabbit polyclonal to PDGF Receptor beta |
|||
 Anti-PDGF-D Antibody |
|||
| A01875 | BosterBio | 100ul | EUR 397 |
|
Description: Rabbit Polyclonal Antibody for PDGF-D Antibody (PDGFD) detection. Tested for IHC, WB, ELISA in Human. |
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 Anti-PDGF-C Antibody |
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| A03092 | BosterBio | 100ul | EUR 397 |
|
Description: Rabbit Polyclonal Antibody for PDGF-C Antibody (PDGFC) detection.tested for IHC in Human, Mouse, Rat. |
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 Anti-PDGF-D antibody |
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| STJ96664 | St John's Laboratory | 200 µl | EUR 197 |
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Description: Rabbit polyclonal to PDGF-D. |
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 Anti-PDGF alpha antibody |
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| STJ97793 | St John's Laboratory | 200 µl | EUR 197 |
|
Description: PDGFRalpha is a protein encoded by the PDGFRA gene which is approximately 122,6 kDa. PDGFRalpha is localised to the cell membrane. It is involved in RET signalling, apoptotic pathways in synovial fibroblasts and the GPCR pathway. It is a tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. It either promotes or inhibits cell proliferation and cell migration and plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. PDGFRalpha is widely expressed in the body including platelets, brain and colon. Mutations in the PDGFRA gene may result in gastrointestinal stromal tumor. STJ97793 was developed from clone 7A3 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody detects endogenous levels of PDGFRalpha. |
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Anti-PDGF alpha antibody |
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| STJ97794 | St John's Laboratory | 200 µl | EUR 197 |
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Description: Mouse monoclonal to PDGFRalpha. |
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 Anti-PDGF-C antibody |
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| STJ98770 | St John's Laboratory | 200 µl | EUR 197 |
|
Description: Rabbit polyclonal to PDGF-C. |
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 Anti-PDGF-A antibody |
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| STJ94995 | St John's Laboratory | 200 µl | EUR 197 |
|
Description: Rabbit polyclonal to PDGF-A. |
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 Anti-PDGF-B antibody |
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| STJ94996 | St John's Laboratory | 200 µl | EUR 197 |
|
Description: PDGF-B a protein encoded by the PDGFB gene which is approximately 27,2 kDa. PDGF-B is secreted into the extracellular space. It is involved in RET signalling, apoptotic pathways, GAB1 signalosome and the GPCR pathway. It is a growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. It is required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. It also plays an important role in wound healing. PDGF-B is expressed at high levels in the heart, brain, placenta and foetal kidney. Mutations in the PDGFB gene may result in basal ganglia calcification and familial meningioma. STJ94996 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of PDGF-B protein. |
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 Polyclonal Goat anti-GST α-form |
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| GST-ANTI-1 | Detroit R&D | 50 uL | EUR 280 |
 Polyclonal Goat anti-GST μ-form |
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| GST-ANTI-2 | Detroit R&D | 50 uL | EUR 280 |
 Polyclonal Goat anti-GST p-form |
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| GST-ANTI-3 | Detroit R&D | 50 uL | EUR 280 |
 PDGF, CF Human |
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| PR15024CF | Neuromics | 5 ug | EUR 1453 |
 PDGF - A Human |
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| PR27059 | Neuromics | 5 ug | EUR 191 |
 PDGF - B Human |
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| PR27060 | Neuromics | 5 ug | EUR 191 |
 PDGF - AA Human |
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| PR27061 | Neuromics | 2 ug | EUR 191 |
 PDGF - AB Human |
|||
| PR27062 | Neuromics | 2 ug | EUR 191 |
PDGF-BB, human |
|||
| RC216-21 | Bio Basic | 2ug | EUR 104.38 |
PDGF-BB, Human |
|||
| HY-P7055 | MedChemExpress | 10ug | EUR 268 |
) Anti-PDGF Receptor beta (4C12) |
|||
| YF-MA14651 | Abfrontier | 100 ug | EUR 363 |
|
Description: Mouse monoclonal to PDGF Receptor beta |
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 Anti-PDGF beta/PDGFB Antibody |
|||
| A00348 | BosterBio | 100ug/vial | EUR 294 |
Anti-PDGF beta/PDGFB Antibody |
|||
| PB9311 | BosterBio | 100ug/vial | EUR 294 |
 PDGF/ Rat PDGF ELISA Kit |
|||
| ELA-E0528r | Lifescience Market | 96 Tests | EUR 886 |
 PDGF antibody |
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| 20R-PG003 | Fitzgerald | 1 mg | EUR 836 |
|
Description: Goat polyclonal PDGF antibody |
|||
 PDGF BB |
|||
| LF-PR012 | Abfrontier | 10 ug | EUR 234 |
|
Description: PDGF BB protein |
|||
 PDGF AA |
|||
| LF-PR026 | Abfrontier | 10 ug | EUR 210 |
|
Description: PDGF AA protein |
|||
 PDGF-BB |
|||
| PR15027 | Neuromics | 50 ug | EUR 396 |
 PDGF-C |
|||
| GT15151 | Neuromics | 100 ug | EUR 526 |
PDGF-BB |
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| E21-199 | EnoGene | 10ug | EUR 343 |
 PDGF Antagonist |
|||
| H-8650.0001 | Bachem | 1.0mg | EUR 357 |
|
Description: Sum Formula: C77H122N20O17; CAS# [143784-00-3] |
|||
PDGF Antagonist |
|||
| H-8650.0005 | Bachem | 5.0mg | EUR 1336 |
|
Description: Sum Formula: C77H122N20O17; CAS# [143784-00-3] |
|||
) Anti-PDGF Receptor alpha (2D2-1A11) |
|||
| YF-MA14649 | Abfrontier | 100 ug | EUR 363 |
|
Description: Mouse monoclonal to PDGF Receptor alpha |
|||
) Anti-PDGF Receptor alpha (4H1-1C9) |
|||
| YF-MA14650 | Abfrontier | 100 ug | EUR 363 |
|
Description: Mouse monoclonal to PDGF Receptor alpha |
|||
) anti-PDGF Receptor β (Phospho-Tyr579) |
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| LF-PA0033 | Abfrontier | 100 ul | EUR 334 |
|
Description: Rabbit polyclonal to PDGF Receptor β (Phospho-Tyr579) |
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) anti-PDGF Receptor β (Phospho-Tyr716) |
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| LF-PA0035 | Abfrontier | 100 ul | EUR 334 |
|
Description: Rabbit polyclonal to PDGF Receptor β (Phospho-Tyr716) |
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) anti-PDGF Receptor β (Phospho-Tyr740) |
|||
| LF-PA0036 | Abfrontier | 100 ul | EUR 334 |
|
Description: Rabbit polyclonal to PDGF Receptor β (Phospho-Tyr740) |
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) anti-PDGF Receptor β (Phospho-Tyr771) |
|||
| LF-PA0038 | Abfrontier | 100 ul | EUR 334 |
|
Description: Rabbit polyclonal to PDGF Receptor β (Phospho-Tyr771) |
|||
) anti-PDGF Receptor β (Phospho-Tyr857) |
|||
| LF-PA0039 | Abfrontier | 100 ul | EUR 334 |
|
Description: Rabbit polyclonal to PDGF Receptor β (Phospho-Tyr857) |
|||
) anti-PDGF Receptor β (Phospho-Tyr1009) |
|||
| LF-PA0040 | Abfrontier | 100 ul | EUR 334 |
|
Description: Rabbit polyclonal to PDGF Receptor β (Phospho-Tyr1009) |
|||
) anti-PDGF Receptor β (Phospho-Tyr1021) |
|||
| LF-PA0041 | Abfrontier | 100 ul | EUR 334 |
|
Description: Rabbit polyclonal to PDGF Receptor β (Phospho-Tyr1021) |
|||
anti-PDGF Receptor β (Phospho-Tyr1021) |
|||
| LF-PA0094 | Abfrontier | 100 ul | EUR 334 |
|
Description: Rabbit polyclonal to PDGF Receptor β (Phospho-Tyr1021) |
|||
) anti-PDGF Receptor β (Ab-752) |
|||
| LF-PA20392 | Abfrontier | 100 ul | EUR 334 |
|
Description: Rabbit polyclonal to PDGF Receptor β |
|||
) anti-PDGF Receptor β (Phospho-Tyr751) |
|||
| LF-PA20626 | Abfrontier | 100 ul | EUR 354 |
|
Description: Rabbit polyclonal to PDGF Receptor β (Phospho-Tyr751) |
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) anti-PDGF Receptor β (Ab-751) |
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| LF-PA20719 | Abfrontier | 100 ul | EUR 334 |
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Description: Rabbit polyclonal to PDGF Receptor β |
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 Anti-PDGF Receptor beta/PDGFRB Antibody |
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| A00096-1 | BosterBio | 100ug/vial | EUR 334 |
 Anti-PDGF Receptor alpha/PDGFRA Antibody |
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| PA1678 | BosterBio | 100ug/vial | EUR 334 |
Anti-PDGF Receptor alpha/PDGFRA Antibody |
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| PB9771 | BosterBio | 100ug/vial | EUR 334 |
 PDGF-CC, human recombinant |
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| 7183-10 | Biovision | EUR 207 | |
PDGF-CC, human recombinant |
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| 7183-50 | Biovision | EUR 675 | |
 PDGF ELISA KIT|Human |
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| EF007049 | Lifescience Market | 96 Tests | EUR 689 |
 PDGF-AA, human recombinant |
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| 4482-10 | Biovision | EUR 332 | |
PDGF-AA, human recombinant |
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| 4482-1000 | Biovision | EUR 6955 | |
PDGF-AA, human recombinant |
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| 4482-50 | Biovision | EUR 936 | |
 PDGF-AB, human recombinant |
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| 4485-10 | Biovision | EUR 332 | |
PDGF-AB, human recombinant |
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| 4485-1000 | Biovision | EUR 6955 | |
PDGF-AB, human recombinant |
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| 4485-50 | Biovision | EUR 936 | |
PDGF-BB, human recombinant |
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| 4488-10 | Biovision | EUR 332 | |
PDGF-BB, human recombinant |
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| 4488-1000 | Biovision | EUR 6955 | |
PDGF-BB, human recombinant |
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| 4488-50 | Biovision | EUR 936 | |
Recombinant Human PDGF-BB |
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| SJA04-01 | Amyotop | 10µg/vial | EUR 256 |
Human PDGF-BB Protein |
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| abx060208-100ug | Abbexa | 100 ug | EUR 523 |
Human PDGF-BB Protein |
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| abx060258-100ug | Abbexa | 100 ug | EUR 523 |
 Human PDGF ELISA Kit |
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| EHP0040 | Abclonal | 96Tests | EUR 521 |
rec PDGF BB (human) |
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| H-7530.0002 | Bachem | 2.0µg | EUR 162 |
rec PDGF BB (human) |
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| H-7530.0010 | Bachem | 10.0µg | EUR 381 |
) rec PDGF AA (human) |
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| H-7640.0002 | Bachem | 2.0µg | EUR 162 |
rec PDGF AA (human) |
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| H-7640.0010 | Bachem | 10.0µg | EUR 381 |
 PDGF-AB/ Rat PDGF- AB ELISA Kit |
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| ELA-E0112r | Lifescience Market | 96 Tests | EUR 886 |
PDGF-BB/ Rat PDGF- BB ELISA Kit |
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| ELA-E0633r | Lifescience Market | 96 Tests | EUR 886 |
) Anti-PDGF Receptor Beta Antibody (Monoclonal, 42G12) |
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| M00096 | BosterBio | 100ug/vial | EUR 397 |
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Description: Mouse Monoclonal PDGF Receptor Beta Antibody (Monoclonal, 42G12). Validated in IHC, WB and tested in Mouse, Rat. |
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 Anti-PDGF Receptor beta Rabbit Monoclonal Antibody |
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| M00096-1 | BosterBio | 100ug/vial | EUR 397 |
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Description: Rabbit Monoclonal PDGF Receptor beta Antibody. Validated in IP, IF, IHC, ICC, WB and tested in Human, Mouse, Rat. |
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 PDGF-AB ELISA KIT|Human |
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| EF000111 | Lifescience Market | 96 Tests | EUR 689 |
PDGF-BB ELISA KIT|Human |
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| EF000205 | Lifescience Market | 96 Tests | EUR 689 |
 PDGF-AA ELISA KIT|Human |
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| EF007050 | Lifescience Market | 96 Tests | EUR 689 |
 Human PDGF Signaling Primer Library |
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| HPDGF-I | Real Time Primers | 1 set | EUR 548 |
 Human PDGF receptor ELISA kit |
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| E01P0755-192T | BlueGene | 192 tests | EUR 1270 |
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Description: A sandwich ELISA for quantitative measurement of Human PDGF receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Human PDGF receptor ELISA kit |
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| E01P0755-48 | BlueGene | 1 plate of 48 wells | EUR 520 |
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Description: A sandwich ELISA for quantitative measurement of Human PDGF receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Human PDGF receptor ELISA kit |
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| E01P0755-96 | BlueGene | 1 plate of 96 wells | EUR 685 |
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Description: A sandwich ELISA for quantitative measurement of Human PDGF receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 Human PDGF-AB ELISA kit |
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| LF-EK50325 | Abfrontier | 1×96T | EUR 648 |
 Recombinant Human PDGF-CC Protein |
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| PROTQ9NRA1-1 | BosterBio | 20ug | EUR 317 |
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Description: The platelet-derived growth factor (PDGF) family of heparin-binding growth factors consists of five known members, denoted PDGF-AA, PDGF-BB, PDGF-AB, PDGF-CC and PDGF-DD. The mature and active form of these proteins, an anti-parallel disulfide-linked dimer of two 12-14 kDa polypeptide chains, is obtained through proteolytic processing of biologically inactive precursor proteins, which contain an N-terminal CUB domain and a PDGF/VEGF homologous domain. The PDGFs interact with two related protein tyrosine kinase receptors, PDGFR-α and PDGFR-β, and are potent mitogens for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and certain tumor cells. They play an important role in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubules epithelial cell development. Mature PDGFs are stored in platelet α-granules and are released upon platelet activation. PDGF-AA, -AB, -BB and –CC signal primarily through the PDGF-Rα receptor, whereas PDGF-DD interacts almost exclusively with the PDGF-Rβ receptor. Recombinant human PDGF-CC is a 25kDa protein consisting of two identical disulfide-linked 114 amino-acid polypeptide chains. |
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Human PDGF-BB ELISA Kit |
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| RK04112 | Abclonal | 96 Tests | EUR 521 |
Recombinant Human PDGF-BB Protein |
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| RP00834 | Abclonal | 10 μg | EUR 221 |
Recombinant Human PDGF-BB Protein |
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| PROTP01127-4 | BosterBio | 10ug | EUR 317 |
|
Description: PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-BB is a 24.3 kDa disulfide-linked homodimer of two B chains (218 total amino acids). |
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 Recombinant Human PDGF-AA Protein |
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| PROTP04085-4 | BosterBio | 10ug | EUR 317 |
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Description: PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-AA is a 28.5 kDa disulfide-linked homodimer of two A chains (250 total amino acids). |
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 Recombinant Human PDGF-AB Protein |
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| PROTP20033-2 | BosterBio | 10ug | EUR 317 |
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Description: PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-AB is a 25.5 kDa disulfide-linked dimer, consisting of one A chain and one B chains (234 total amino acids). |
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PDGF-BB (P.pastoris-expressed), Human |
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| HY-P7055A | MedChemExpress | 10ug | EUR 268 |
, Human) PDGF-CC (HEK293-expressed), Human |
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| HY-P7279 | MedChemExpress | 10ug | EUR 223 |
