Dysregulated mesenchymal PDGFR-β drives kidney fibrosis
Kidney fibrosis is characterised by growth and activation of platelet-derived development issue receptor-β (PDGFR-β)-positive mesenchymal cells. To review the implications of PDGFR-β activation, we developed a mannequin of major renal fibrosis utilizing transgenic mice with PDGFR-β activation particularly in renal mesenchymal cells, driving their pathological proliferation and phenotypic change towards myofibroblasts.
This resulted in progressive mesangioproliferative glomerulonephritis, mesangial sclerosis, and interstitial fibrosis with progressive anemia as a consequence of lack of erythropoietin manufacturing by fibroblasts.
Fibrosis induced secondary tubular epithelial harm at later levels, coinciding with microinflammation, and aggravated the development of hypertensive and obstructive nephropathy.
Human Platelet-Derived Growth Factor-BB,PDGF-BB ELISA kit
Inhibition of PDGFR activation reversed fibrosis extra successfully within the tubulointerstitium in comparison with glomeruli. Gene expression signatures in mice with PDGFR-β activation resembled these present in sufferers.
In conclusion, PDGFR-β activation alone is ample to induce progressive renal fibrosis and failure, mimicking key facets of continual kidney illness in people. Our information present direct proof that fibrosis per se can drive continual organ harm and set up a mannequin of major fibrosis permitting particular research focusing on fibrosis development and regression.
AFC1 Compound Attenuated MI/R-Induced Ventricular Transforming through Inhibiting PDGFR and STAT Pathway.
Background: Efficient interventions to enhance the result of sufferers subjected to myocardial ischemia reperfusion (MI/R) are pressing in medical settings. Tanshinone IIA (TSA) is reported to attenuate myocardial harm and enhance ventricular reworking publish MI/R. Right here, we evaluated the efficacy of AFC1 compound that’s much like TSA construction in murine MI/R fashions.
PDGF-BB (P.pastoris-expressed), Human
We discovered that AFC1 had a comparable impact of enhancing murine cardiac perform after MI/R whereas it was superior to TSA in security profile. Administration of AFC1 diminished reactive oxygen species (ROS) manufacturing, inflammatory cells infiltration, and the expression of platelet derived development issue receptors (PDGFR) in infarcted myocardium.
Remedy with AFC1 additionally attenuated MI/R-induced cardiac reworking and contributed to the restoration of cardiac perform. Moreover, AFC1 reversed the elevation of PDGFR expression induced by PDGF-AB in each neonatal rat cardiomyocytes (NCMs) and neonatal rat cardiac fibroblasts (NCFs) and suppressed PDGF-AB induced NCM hypertrophy through STAT3 pathway and NCF collagen synthesis by means of p38-MAPK signaling in vitro. Equally, AFC1 could contribute to the restoration of cardiac perform in mice publish MI/R through suppressing STAT signaling.
Our outcomes confirmed that AFC1 exerts anti-hypertrophic and anti-fibrotic results towards MI/R-induced cardiac reworking, and counsel that AFC1 could have a promising potential in enhancing the result of sufferers who suffered from MI/R.
Human Complement Factor Bb (CFB-Bb) Antibody
PDGF-BB/ Rat PDGF- BB ELISA Kit |
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| ELA-E0633r | Lifescience Market | 96 Tests | EUR 886 |
Polyclonal PDGF-BB Antibody |
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| APR08990G | Leading Biology | 0.1mg | EUR 484 |
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Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PDGF-BB . This antibody is tested and proven to work in the following applications: |
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Polyclonal PDGF-BB Antibody |
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| APR00412G | Leading Biology | 0.1mg | EUR 484 |
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Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PDGF-BB . This antibody is tested and proven to work in the following applications: |
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PDGF-BB, human |
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| RC216-21 | Bio Basic | 2ug | EUR 104.38 |
PDGF-BB, Human |
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| HY-P7055 | MedChemExpress | 10ug | EUR 268 |
PDGF-BB, Mouse |
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| HY-P7087 | MedChemExpress | 100ug | EUR 946 |
PDGF-BB, Rat |
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| HY-P7278 | MedChemExpress | 50ug | EUR 383 |
PDGF-BB, CF |
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| PR15026CF | Neuromics | 50 ug | EUR 1087 |
PDGF-BB, CF |
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| PR15027CF | Neuromics | 50 ug | EUR 396 |
rHu PDGF-BB |
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| AK8292-0002 | Akron Biotech | 2µg | Ask for price |
rHu PDGF-BB |
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| AK8292-0010 | Akron Biotech | 10µg | Ask for price |
rHu PDGF-BB |
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| AK8292-0100 | Akron Biotech | 100µg | Ask for price |
rHu PDGF-BB |
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| AK8292-1000 | Akron Biotech | 1mg | Ask for price |
PDGF BB protein |
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| 30R-2611 | Fitzgerald | 10 ug | EUR 359 |
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Description: Purified recombinant Human PDGF BB protein |
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PDGF BB protein |
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| 30R-2612 | Fitzgerald | 10 ug | EUR 302 |
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Description: Purified recombinant Mouse PDGF BB protein |
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PDGF BB protein |
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| 30R-AP004 | Fitzgerald | 2 ug | EUR 133 |
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Description: Purified recombinant Human PDGF BB protein |
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PDGF BB protein |
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| 30R-AP051 | Fitzgerald | 10 ug | EUR 273 |
|
Description: Purified recombinant Human PDGF BB protein |
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anti-PDGF BB |
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| YF-PA13686 | Abfrontier | 50 ug | EUR 363 |
|
Description: Mouse polyclonal to PDGF BB |
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anti-PDGF BB |
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| YF-PA24331 | Abfrontier | 50 ul | EUR 334 |
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Description: Mouse polyclonal to PDGF BB |
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Human PDGF-BB Protein |
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| abx060208-100ug | Abbexa | 100 ug | EUR 523 |
Human PDGF-BB Protein |
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| abx060258-100ug | Abbexa | 100 ug | EUR 523 |
rec PDGF BB (human) |
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| H-7530.0002 | Bachem | 2.0µg | EUR 162 |
rec PDGF BB (human) |
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| H-7530.0010 | Bachem | 10.0µg | EUR 381 |
PDGF-BB Recombinant Protein |
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| 11-380 | ProSci | 0.05 mg | EUR 595.25 |
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Description: PDGFs are mitogenic during early developmental stages, driving the proliferation of undifferentiated mesenchyme and some progenitor populations. During later maturation stages, PDGF signalling has been implicated in tissue remodelling and cellular differentiation, and in inductive events involved in patterning and morphogenesis. In addition to driving mesenchymal proliferation, PDGFs have been shown to direct the migration, differentiation and function of a variety of specialised mesenchymal and migratory cell types, both during development and in the adult animal. Other growth factors in this family include vascular endothelial growth factors B and C (VEGF-B, VEGF-C)which are active in angiogenesis and endothelial cell growth, and placenta growth factor (PlGF) which is also active in angiogenesis. PDGF plays a role in embryonic development, cell proliferation, cell migration, and angiogenesis. PDGF is a required element in cellular division for fibroblast, a type of connective tissue cell. PDGF is also known to maintain proliferation of oligodendrocyte progenitor cells. Platelet-derived growth factor subunit B is also known as PDGFB, FLJ12858, PDGF2, SIS, SSV, c-sis, is a member of the platelet-derived growth factor family. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. |
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PDGF-BB Recombinant Protein |
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| 40-607 | ProSci | 0.01 mg | EUR 401 |
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Description: PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet a-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-a and PDGFR-β. PDGFR-a is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-BB is a 24.3 kDa disulfide-linked homodimer of two B chains (218 total amino acids). . |
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PDGF-BB Recombinant Protein |
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| 40-158-0002mg | ProSci | 0.002 mg | EUR 259.25 |
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Description: PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-BB is a 24.3 kDa disulfide-linked homodimer of two B chains (218 total amino acids). |
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PDGF-BB Recombinant Protein |
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| 40-158-001mg | ProSci | 0.01 mg | EUR 364.25 |
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Description: PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-BB is a 24.3 kDa disulfide-linked homodimer of two B chains (218 total amino acids). |
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PDGF-BB Recombinant Protein |
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| 40-458-0002mg | ProSci | 0.002 mg | EUR 259.25 |
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Description: PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant murine PDGF-BB is a 24.4 kDa disulfide-linked homodimer of two B chains (218 total amino acids). |
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PDGF-BB Recombinant Protein |
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| 40-458-001mg | ProSci | 0.01 mg | EUR 364.25 |
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Description: PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant murine PDGF-BB is a 24.4 kDa disulfide-linked homodimer of two B chains (218 total amino acids). |
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Recombinant Human PDGF-BB |
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| SJA04-01 | Amyotop | 10µg/vial | EUR 256 |
PDGF-BB, human recombinant |
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| 4488-10 | Biovision | EUR 332 | |
PDGF-BB, human recombinant |
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| 4488-1000 | Biovision | EUR 6955 | |
PDGF-BB, human recombinant |
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| 4488-50 | Biovision | EUR 936 | |
PDGF-BB, murine recombinant |
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| 4489-10 | Biovision | EUR 267 | |
PDGF-BB, murine recombinant |
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| 4489-1000 | Biovision | EUR 5362 | |
PDGF-BB, murine recombinant |
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| 4489-50 | Biovision | EUR 729 | |
PDGF-BB Recombinant Protein |
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| 91-179 | ProSci | 0.05 mg | EUR 684.5 |
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Description: Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound. |
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Polyclonal PDGF-BB Antibody (aa21-70) |
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| APR08991G | Leading Biology | 0.05ml | EUR 484 |
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Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PDGF-BB (aa21-70). This antibody is tested and proven to work in the following applications: |
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Polyclonal PDGF-BB Antibody (C-Terminus) |
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| APR08992G | Leading Biology | 0.05mg | EUR 484 |
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Description: A polyclonal antibody raised in Goat that recognizes and binds to Human PDGF-BB (C-Terminus). This antibody is tested and proven to work in the following applications: |
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Human PDGF-BB ELISA Kit |
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| RK04112 | Abclonal | 96 Tests | EUR 521 |
Recombinant Human PDGF-BB Protein |
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| RP00834 | Abclonal | 10 μg | EUR 221 |
Sheep PDGF-BB ELISA Kit |
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| ESP0050 | Abclonal | 96Tests | EUR 521 |
Recombinant Human PDGF-BB Protein |
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| PROTP01127-4 | BosterBio | 10ug | EUR 317 |
|
Description: PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-BB is a 24.3 kDa disulfide-linked homodimer of two B chains (218 total amino acids). |
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Recombinant Murine PDGF-BB Protein |
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| PROTP31240-1 | BosterBio | 10ug | EUR 317 |
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Description: PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant murine PDGF-BB is a 24.4 kDa disulfide-linked homodimer of two B chains (218 total amino acids). |
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PDGF-BB (P.pastoris-expressed), Human |
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| HY-P7055A | MedChemExpress | 10ug | EUR 268 |
Anserini PDGF-BB ELISA Kit |
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| EAP0634 | Abclonal | 96Tests | EUR 521 |
Rat PDGF-BB ELISA Kit |
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| ERP0050 | Abclonal | 96Tests | EUR 521 |
Rat PDGF-BB ELISA Kit |
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| ERP0634 | Abclonal | 96Tests | EUR 521 |
Rabbit PDGF-BB ELISA Kit |
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| ERTP0050 | Abclonal | 96Tests | EUR 521 |
Rabbit PDGF-BB ELISA Kit |
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| ERTP0634 | Abclonal | 96Tests | EUR 521 |
Monkey PDGF-BB ELISA Kit |
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| EMKP0050 | Abclonal | 96Tests | EUR 521 |
Mouse PDGF-BB ELISA Kit |
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| EMP0050 | Abclonal | 96Tests | EUR 521 |
Mouse PDGF-BB ELISA Kit |
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| EMP0634 | Abclonal | 96Tests | EUR 521 |
Porcine PDGF-BB ELISA Kit |
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| EPP0050 | Abclonal | 96Tests | EUR 521 |
Porcine PDGF-BB ELISA Kit |
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| EPP0634 | Abclonal | 96Tests | EUR 521 |
Human PDGF-BB ELISA Kit |
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| EHP0050 | Abclonal | 96Tests | EUR 521 |
Human PDGF-BB ELISA Kit |
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| EHP0634 | Abclonal | 96Tests | EUR 521 |
Chicken PDGF-BB ELISA Kit |
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| ECKP0050 | Abclonal | 96Tests | EUR 521 |
Canine PDGF-BB ELISA Kit |
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| ECP0050 | Abclonal | 96Tests | EUR 521 |
Canine PDGF-BB ELISA Kit |
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| ECP0634 | Abclonal | 96Tests | EUR 521 |
Bovine PDGF-BB ELISA Kit |
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| EBP0050 | Abclonal | 96Tests | EUR 521 |
Bovine PDGF-BB ELISA Kit |
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| EBP0634 | Abclonal | 96Tests | EUR 521 |
Goat PDGF-BB ELISA Kit |
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| EGTP0050 | Abclonal | 96Tests | EUR 521 |
Goat PDGF-BB ELISA Kit |
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| EGTP0634 | Abclonal | 96Tests | EUR 521 |
PDGF-BB, human recombinant protein |
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| P1047-.01 | ApexBio | 10 µg | EUR 313 |
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Description: The platelet-derived growth factor BB (PDGF-BB) is a member of the PDGF family and is a disulfide-linked homodimer. PDGF family consists of proteins PDGF-A, -B that form three disulfide-linked homodimers (PDGF-AA, -BB and -AB). |
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PDGF-BB, human recombinant protein |
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| P1047-.05 | ApexBio | 50 µg | EUR 877 |
|
Description: The platelet-derived growth factor BB (PDGF-BB) is a member of the PDGF family and is a disulfide-linked homodimer. PDGF family consists of proteins PDGF-A, -B that form three disulfide-linked homodimers (PDGF-AA, -BB and -AB). |
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PDGF-BB, human recombinant protein |
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| P1047-1 | ApexBio | 1 mg | EUR 6522 |
|
Description: The platelet-derived growth factor BB (PDGF-BB) is a member of the PDGF family and is a disulfide-linked homodimer. PDGF family consists of proteins PDGF-A, -B that form three disulfide-linked homodimers (PDGF-AA, -BB and -AB). |
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PDGF-BB, murine recombinant protein |
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| P1048-.01 | ApexBio | 10 µg | EUR 313 |
|
Description: The platelet-derived growth factor BB (PDGF-BB) is a member of the PDGF family and is a disulfide-linked homodimer. PDGF family consists of proteins PDGF-A, -B that form three disulfide-linked homodimers (PDGF-AA, -BB and -AB). |
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PDGF-BB, murine recombinant protein |
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| P1048-.05 | ApexBio | 50 µg | EUR 877 |
|
Description: The platelet-derived growth factor BB (PDGF-BB) is a member of the PDGF family and is a disulfide-linked homodimer. PDGF family consists of proteins PDGF-A, -B that form three disulfide-linked homodimers (PDGF-AA, -BB and -AB). |
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PDGF-BB, murine recombinant protein |
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| P1048-1 | ApexBio | 1 mg | EUR 6522 |
|
Description: The platelet-derived growth factor BB (PDGF-BB) is a member of the PDGF family and is a disulfide-linked homodimer. PDGF family consists of proteins PDGF-A, -B that form three disulfide-linked homodimers (PDGF-AA, -BB and -AB). |
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rHu PDGF-BB (yeast) (cGMP) |
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| AK8274-1000 | Akron Biotech | 1mg | Ask for price |
PDGF-BB ELISA KIT|Human |
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| EF000205 | Lifescience Market | 96 Tests | EUR 689 |
Recombinant Human Platelet-Derived Growth Factor BB/PDGF-BB |
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| C199-10ug | Novoprotein | 10ug | EUR 202 |
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Description: Lyophilized from a 0.2 μm filtered solution of 4mM HCl. |
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Recombinant Human Platelet-Derived Growth Factor BB/PDGF-BB |
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| C199-1mg | Novoprotein | 1mg | EUR 2283 |
|
Description: Lyophilized from a 0.2 μm filtered solution of 4mM HCl. |
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Recombinant Human Platelet-Derived Growth Factor BB/PDGF-BB |
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| C199-500ug | Novoprotein | 500ug | EUR 1613 |
|
Description: Lyophilized from a 0.2 μm filtered solution of 4mM HCl. |
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Recombinant Human Platelet-Derived Growth Factor BB/PDGF-BB |
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| C199-50ug | Novoprotein | 50ug | EUR 496 |
|
Description: Lyophilized from a 0.2 μm filtered solution of 4mM HCl. |
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Genorise® Chicken PDGF-BB Polyclonal Antibody |
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| GR128034 | Genorise Scientific | 100 µg | EUR 398 |
Genorise® Sheep PDGF-BB Polyclonal Antibody |
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| GR130039 | Genorise Scientific | 100 µg | EUR 398 |
Genorise® Mouse PDGF-BB Polyclonal Antibody |
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| GR131039 | Genorise Scientific | 100 µg | EUR 398 |
Genorise® Rat PDGF-BB Polyclonal Antibody |
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| GR132039 | Genorise Scientific | 100 µg | EUR 398 |
Genorise® Feline PDGF-BB Polyclonal Antibody |
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| GR195039 | Genorise Scientific | 100 µg | EUR 398 |
Cadherin-11 binds to PDGFRβ and enhances cell proliferation and tissue regeneration through the PDGFR-AKT signaling axis.
Intercellular adhesion by means of homotypic interplay between cadherins regulates a number of mobile processes together with cytoskeletal group, proliferation, and survival. On this paper, we offer proof that cadherin-11 (CDH11) binds to and promotes cell proliferation each in vitro and in vivo in synergy with the platelet-derived development issue receptor beta (PDGFRβ).
Engagement of CDH11 elevated the sensitivity of cells to PDGF-BB by 10- to 100-fold, leading to fast and sustained phosphorylation of AKT, finally selling and cell proliferation and tissue regeneration.
Certainly, wound therapeutic experiments confirmed that therapeutic was severely compromised in Cdh11-/- mice, as evidenced by considerably decreased proliferation, AKT phosphorylation, and extracellular matrix (ECM) synthesis of dermal cells.
Human Glycogen phosphorylase BB,GP-BB ELISA Kit
Our outcomes shed gentle into understanding how intercellular adhesion can promote cell proliferation and will have implications for tissue regeneration and most cancers development.
anti-PDGF BB |
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| YF-PA13686 | Abfrontier | 50 ug | EUR 363 |
|
Description: Mouse polyclonal to PDGF BB |
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anti-PDGF AA |
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| YF-PA24330 | Abfrontier | 50 ul | EUR 334 |
|
Description: Mouse polyclonal to PDGF AA |
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anti-PDGF BB |
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| YF-PA24331 | Abfrontier | 50 ul | EUR 334 |
|
Description: Mouse polyclonal to PDGF BB |
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Genorise® Biotinylated Bovine PDGF polyclonal antibody |
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| GR134004 | Genorise Scientific | 50 µg | EUR 398 |
Genorise® Biotinylated Feline PDGF Polyclonal Antibody |
|||
| GR196037 | Genorise Scientific | 100 µg | EUR 398 |
Genorise® Biotinylated Hamster PDGF Polyclonal Antibody |
|||
| GR209037 | Genorise Scientific | 100 µg | EUR 398 |
Anti-PDGF-D Antibody |
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| A01875 | BosterBio | 100ul | EUR 397 |
|
Description: Rabbit Polyclonal Antibody for PDGF-D Antibody (PDGFD) detection. Tested for IHC, WB, ELISA in Human. |
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Anti-PDGF-C Antibody |
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| A03092 | BosterBio | 100ul | EUR 397 |
|
Description: Rabbit Polyclonal Antibody for PDGF-C Antibody (PDGFC) detection.tested for IHC in Human, Mouse, Rat. |
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Anti-PDGF-D antibody |
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| STJ96664 | St John's Laboratory | 200 µl | EUR 197 |
|
Description: Rabbit polyclonal to PDGF-D. |
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Anti-PDGF alpha antibody |
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| STJ97793 | St John's Laboratory | 200 µl | EUR 197 |
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Description: PDGFRalpha is a protein encoded by the PDGFRA gene which is approximately 122,6 kDa. PDGFRalpha is localised to the cell membrane. It is involved in RET signalling, apoptotic pathways in synovial fibroblasts and the GPCR pathway. It is a tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. It either promotes or inhibits cell proliferation and cell migration and plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. PDGFRalpha is widely expressed in the body including platelets, brain and colon. Mutations in the PDGFRA gene may result in gastrointestinal stromal tumor. STJ97793 was developed from clone 7A3 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody detects endogenous levels of PDGFRalpha. |
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Anti-PDGF alpha antibody |
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| STJ97794 | St John's Laboratory | 200 µl | EUR 197 |
|
Description: Mouse monoclonal to PDGFRalpha. |
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Anti-PDGF-C antibody |
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| STJ98770 | St John's Laboratory | 200 µl | EUR 197 |
|
Description: Rabbit polyclonal to PDGF-C. |
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Anti-PDGF-A antibody |
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| STJ94995 | St John's Laboratory | 200 µl | EUR 197 |
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Description: Rabbit polyclonal to PDGF-A. |
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Anti-PDGF-B antibody |
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| STJ94996 | St John's Laboratory | 200 µl | EUR 197 |
|
Description: PDGF-B a protein encoded by the PDGFB gene which is approximately 27,2 kDa. PDGF-B is secreted into the extracellular space. It is involved in RET signalling, apoptotic pathways, GAB1 signalosome and the GPCR pathway. It is a growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. It is required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. It also plays an important role in wound healing. PDGF-B is expressed at high levels in the heart, brain, placenta and foetal kidney. Mutations in the PDGFB gene may result in basal ganglia calcification and familial meningioma. STJ94996 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of PDGF-B protein. |
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anti-PDGF Receptor alpha |
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| YF-PA13687 | Abfrontier | 50 ug | EUR 363 |
|
Description: Mouse polyclonal to PDGF Receptor alpha |
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anti-PDGF Receptor alpha |
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| YF-PA13688 | Abfrontier | 100 ug | EUR 403 |
|
Description: Rabbit polyclonal to PDGF Receptor alpha |
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anti-PDGF Receptor beta |
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| YF-PA13689 | Abfrontier | 50 ug | EUR 363 |
|
Description: Mouse polyclonal to PDGF Receptor beta |
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anti-PDGF Receptor beta |
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| YF-PA13690 | Abfrontier | 100 ug | EUR 403 |
|
Description: Rabbit polyclonal to PDGF Receptor beta |
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Polyclonal Goat anti-GST α-form |
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| GST-ANTI-1 | Detroit R&D | 50 uL | EUR 280 |
Polyclonal Goat anti-GST μ-form |
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| GST-ANTI-2 | Detroit R&D | 50 uL | EUR 280 |
Polyclonal Goat anti-GST p-form |
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| GST-ANTI-3 | Detroit R&D | 50 uL | EUR 280 |
Genorise® Biotinylated Bovine PDGF-AA polyclonal antibody |
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| GR134005 | Genorise Scientific | 50 µg | EUR 398 |
Genorise® Biotinylated Bovine PDGF-BB polyclonal antibody |
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| GR134006 | Genorise Scientific | 50 µg | EUR 398 |
Genorise® Biotinylated Feline PDGF-AA Polyclonal Antibody |
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| GR196038 | Genorise Scientific | 100 µg | EUR 398 |
Genorise® Biotinylated Feline PDGF-BB Polyclonal Antibody |
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| GR196039 | Genorise Scientific | 100 µg | EUR 398 |
Genorise® Biotinylated Hamster PDGF-AA Polyclonal Antibody |
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| GR209038 | Genorise Scientific | 100 µg | EUR 398 |
Genorise® Biotinylated Hamster PDGF-BB Polyclonal Antibody |
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| GR209039 | Genorise Scientific | 100 µg | EUR 398 |
Anti-PDGF beta/PDGFB Antibody |
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| PB9311 | BosterBio | 100ug/vial | EUR 294 |
Anti-PDGF beta/PDGFB Antibody |
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| A00348 | BosterBio | 100ug/vial | EUR 294 |
Anti-PDGF Receptor beta (4C12) |
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| YF-MA14651 | Abfrontier | 100 ug | EUR 363 |
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Description: Mouse monoclonal to PDGF Receptor beta |
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PDGF-BB, human |
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| RC216-21 | Bio Basic | 2ug | EUR 104.38 |
PDGF-BB, Human |
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| HY-P7055 | MedChemExpress | 10ug | EUR 268 |
PDGF, CF Human |
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| PR15024CF | Neuromics | 5 ug | EUR 1453 |
PDGF - A Human |
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| PR27059 | Neuromics | 5 ug | EUR 191 |
PDGF - B Human |
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| PR27060 | Neuromics | 5 ug | EUR 191 |
PDGF - AA Human |
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| PR27061 | Neuromics | 2 ug | EUR 191 |
PDGF - AB Human |
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| PR27062 | Neuromics | 2 ug | EUR 191 |
PDGF/ Rat PDGF ELISA Kit |
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| ELA-E0528r | Lifescience Market | 96 Tests | EUR 886 |
Anti-PDGF Receptor alpha/PDGFRA Antibody |
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| PA1678 | BosterBio | 100ug/vial | EUR 334 |
Anti-PDGF Receptor alpha/PDGFRA Antibody |
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| PB9771 | BosterBio | 100ug/vial | EUR 334 |
Anti-PDGF Receptor beta/PDGFRB Antibody |
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| A00096-1 | BosterBio | 100ug/vial | EUR 334 |
anti-PDGF Receptor β (Phospho-Tyr579) |
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| LF-PA0033 | Abfrontier | 100 ul | EUR 334 |
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Description: Rabbit polyclonal to PDGF Receptor β (Phospho-Tyr579) |
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anti-PDGF Receptor β (Phospho-Tyr716) |
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| LF-PA0035 | Abfrontier | 100 ul | EUR 334 |
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Description: Rabbit polyclonal to PDGF Receptor β (Phospho-Tyr716) |
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anti-PDGF Receptor β (Phospho-Tyr740) |
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| LF-PA0036 | Abfrontier | 100 ul | EUR 334 |
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Description: Rabbit polyclonal to PDGF Receptor β (Phospho-Tyr740) |
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anti-PDGF Receptor β (Phospho-Tyr771) |
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| LF-PA0038 | Abfrontier | 100 ul | EUR 334 |
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Description: Rabbit polyclonal to PDGF Receptor β (Phospho-Tyr771) |
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anti-PDGF Receptor β (Phospho-Tyr857) |
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| LF-PA0039 | Abfrontier | 100 ul | EUR 334 |
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Description: Rabbit polyclonal to PDGF Receptor β (Phospho-Tyr857) |
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anti-PDGF Receptor β (Phospho-Tyr1009) |
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| LF-PA0040 | Abfrontier | 100 ul | EUR 334 |
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Description: Rabbit polyclonal to PDGF Receptor β (Phospho-Tyr1009) |
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anti-PDGF Receptor β (Phospho-Tyr1021) |
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| LF-PA0041 | Abfrontier | 100 ul | EUR 334 |
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Description: Rabbit polyclonal to PDGF Receptor β (Phospho-Tyr1021) |
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anti-PDGF Receptor β (Phospho-Tyr1021) |
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| LF-PA0094 | Abfrontier | 100 ul | EUR 334 |
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Description: Rabbit polyclonal to PDGF Receptor β (Phospho-Tyr1021) |
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anti-PDGF Receptor β (Ab-752) |
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| LF-PA20392 | Abfrontier | 100 ul | EUR 334 |
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Description: Rabbit polyclonal to PDGF Receptor β |
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anti-PDGF Receptor β (Phospho-Tyr751) |
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| LF-PA20626 | Abfrontier | 100 ul | EUR 354 |
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Description: Rabbit polyclonal to PDGF Receptor β (Phospho-Tyr751) |
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anti-PDGF Receptor β (Ab-751) |
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| LF-PA20719 | Abfrontier | 100 ul | EUR 334 |
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Description: Rabbit polyclonal to PDGF Receptor β |
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Anti-PDGF Receptor alpha (2D2-1A11) |
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| YF-MA14649 | Abfrontier | 100 ug | EUR 363 |
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Description: Mouse monoclonal to PDGF Receptor alpha |
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Anti-PDGF Receptor alpha (4H1-1C9) |
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| YF-MA14650 | Abfrontier | 100 ug | EUR 363 |
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Description: Mouse monoclonal to PDGF Receptor alpha |
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PDGF-BB |
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| E21-199 | EnoGene | 10ug | EUR 343 |
PDGF-BB |
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| PR15027 | Neuromics | 50 ug | EUR 396 |
PDGF-C |
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| GT15151 | Neuromics | 100 ug | EUR 526 |
PDGF Antagonist |
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| H-8650.0001 | Bachem | 1.0mg | EUR 357 |
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Description: Sum Formula: C77H122N20O17; CAS# [143784-00-3] |
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PDGF Antagonist |
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| H-8650.0005 | Bachem | 5.0mg | EUR 1336 |
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Description: Sum Formula: C77H122N20O17; CAS# [143784-00-3] |
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PDGF BB |
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| LF-PR012 | Abfrontier | 10 ug | EUR 234 |
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Description: PDGF BB protein |
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PDGF AA |
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| LF-PR026 | Abfrontier | 10 ug | EUR 210 |
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Description: PDGF AA protein |
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PDGF antibody |
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| 20R-PG003 | Fitzgerald | 1 mg | EUR 836 |
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Description: Goat polyclonal PDGF antibody |
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Human PDGF ELISA Kit |
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| EHP0040 | Abclonal | 96Tests | EUR 521 |
Human PDGF-BB Protein |
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| abx060208-100ug | Abbexa | 100 ug | EUR 523 |
Human PDGF-BB Protein |
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| abx060258-100ug | Abbexa | 100 ug | EUR 523 |
rec PDGF BB (human) |
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| H-7530.0002 | Bachem | 2.0µg | EUR 162 |
rec PDGF BB (human) |
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| H-7530.0010 | Bachem | 10.0µg | EUR 381 |
rec PDGF AA (human) |
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| H-7640.0002 | Bachem | 2.0µg | EUR 162 |
rec PDGF AA (human) |
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| H-7640.0010 | Bachem | 10.0µg | EUR 381 |
PDGF ELISA KIT|Human |
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| EF007049 | Lifescience Market | 96 Tests | EUR 689 |
Recombinant Human PDGF-BB |
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| SJA04-01 | Amyotop | 10µg/vial | EUR 256 |
PDGF-AA, human recombinant |
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| 4482-10 | Biovision | EUR 332 | |
PDGF-AA, human recombinant |
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| 4482-1000 | Biovision | EUR 6955 | |
PDGF-AA, human recombinant |
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| 4482-50 | Biovision | EUR 936 | |
PDGF-AB, human recombinant |
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| 4485-10 | Biovision | EUR 332 | |
PDGF-AB, human recombinant |
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| 4485-1000 | Biovision | EUR 6955 | |
PDGF-AB, human recombinant |
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| 4485-50 | Biovision | EUR 936 | |
PDGF-BB, human recombinant |
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| 4488-10 | Biovision | EUR 332 | |
PDGF-BB, human recombinant |
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| 4488-1000 | Biovision | EUR 6955 | |
PDGF-BB, human recombinant |
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| 4488-50 | Biovision | EUR 936 | |
PDGF-CC, human recombinant |
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| 7183-10 | Biovision | EUR 207 | |
PDGF-CC, human recombinant |
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| 7183-50 | Biovision | EUR 675 | |
PDGF-AB/ Rat PDGF- AB ELISA Kit |
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| ELA-E0112r | Lifescience Market | 96 Tests | EUR 886 |
PDGF-BB/ Rat PDGF- BB ELISA Kit |
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| ELA-E0633r | Lifescience Market | 96 Tests | EUR 886 |
Anti-PDGF Receptor Beta Antibody (Monoclonal, 42G12) |
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| M00096 | BosterBio | 100ug/vial | EUR 397 |
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Description: Mouse Monoclonal PDGF Receptor Beta Antibody (Monoclonal, 42G12). Validated in IHC, WB and tested in Mouse, Rat. |
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Anti-PDGF Receptor beta Rabbit Monoclonal Antibody |
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| M00096-1 | BosterBio | 100ug/vial | EUR 397 |
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Description: Rabbit Monoclonal PDGF Receptor beta Antibody. Validated in IP, IF, IHC, ICC, WB and tested in Human, Mouse, Rat. |
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Genorise® Anti-Equine PDGF Polyclonal Antibody |
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| GR105192 | Genorise Scientific | 100 ug | EUR 438 |
Genorise® Anti-Canine PDGF Polyclonal Antibody |
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| GR105196 | Genorise Scientific | 100 ug | EUR 438 |
Rabbit anti-Human CD40 IgG, Biotinylated |
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| CD4011-BTN | Alpha Diagnostics | 50 ug | EUR 518 |
Biotinylated Goat anti-Human Eotaxin antibody |
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| 60-5011 | Fitzgerald | 25 ug | EUR 300 |
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Description: Purified Biotinylated Goat anti-Human Eotaxin polyclonal antibody |
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Anti-CHO Biotinylated Concentrate |
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| F017B | Cygnus Technologies | 1 mg | EUR 3145 |
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Description: Anti-CHO Biotinylated Concentrate by Cygnus Technologies is available in Europe via Gentaur. |
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Anti-PON1 Biotinylated Antibody |
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| A00516-Biotin | BosterBio | 50ug/vial | EUR 294 |
Anti-FGF21 Biotinylated Antibody |
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| A00802-Biotin | BosterBio | 50ug/vial | EUR 294 |
