Autophagy induction and PDGFR-β knockdown by siRNA-encapsulated nanoparticles cut back chlamydia trachomatis an infection.

C. trachomatis is the commonest sexually transmitted bacterial an infection on this planet. Though the an infection could be simply managed by means of antibiotics, a number of experiences of scientific isolates which can be proof against antibiotics have prompted us to seek for different methods to handle this illness.

On this paper, we developed a nanoparticle formulation (PDGFR-β siRNA-PEI-PLGA-PEG NP) that may concurrently induce autophagy in human cells and knock down PDGFR-β gene expression, an necessary floor binding protein for C. trachomatis, as a technique to cut back vaginal an infection of C. trachomatis.

PDGFR-β siRNA-PEI-PLGA-PEG NP considerably induced autophagy in human vaginal epithelial cells (VK2/E6E7) 48 hr publish remedy by bettering autophagic degradation exercise with out inflicting irritation, apoptosis or any lower in cell viability. Beclin-1, VPS34 (markers for initiation stage of autophagy), UVRAG, TECPR-1 (markers for degradation stage of autophagy) had been discovered to be considerably upregulated after remedy with PDGFR-β siRNA-PEI-PLGA-PEG NP.

 

 

vegf-a
vegf-a

 

 

Human PDGF-BB Recombinant Protein

200-055 5 µg
EUR 52.5
Description: PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet alpha-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-alpha and PDGFR-beta. PDGFR-alpha is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-beta interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-BB is a 24.3 kDa disulfide-linked homodimer of two B chains (218 total amino acids).

Human PDGF-BB Recombinant Protein

200-055S 2 µg
EUR 47.25
Description: PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet alpha-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-alpha and PDGFR-beta. PDGFR-alpha is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-beta interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-BB is a 24.3 kDa disulfide-linked homodimer of two B chains (218 total amino acids).

Human PDGF-BB Recombinant Protein

200-056 20 µg
EUR 136.5
Description: PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet alpha-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-alpha and PDGFR-beta. PDGFR-alpha is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-beta interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-BB is a 24.3 kDa disulfide-linked homodimer of two B chains (218 total amino acids).

PDGF-BB, human recombinant protein

P1047-.01 10 µg
EUR 222
Description: PDGF-BB, platelet-derived growth factor, expressed in E.Coli.

PDGF-BB, human recombinant protein

P1047-.05 50 µg
EUR 692
Description: PDGF-BB, platelet-derived growth factor, expressed in E.Coli.

PDGF-BB, human recombinant protein

P1047-1 1 mg
EUR 5414
Description: PDGF-BB, platelet-derived growth factor, expressed in E.Coli.

Genorise® Recombinant Human PDGF-BB

GR104258 5 µg
EUR 285

Recombinant Human PDGF-BB Protein (Active)

PKSH032906-10ug 10ug
EUR 178
Description: Human

Recombinant Human PDGF-BB Protein (Active)

PKSH032906-50ug 50ug
EUR 523
Description: Human

Recombinant Rat PDGF-BB

REGFP-1601 10ug Ask for price

Human PDGF-BB Recombinant Protein Lyophilized

IHUPDGFBBRLY10UG each
EUR 535
Description: Human PDGF-BB Recombinant Protein Lyophilized

Human PDGF-BB Recombinant Protein Lyophilized

IHUPDGFBBRLY2UG each
EUR 341
Description: Human PDGF-BB Recombinant Protein Lyophilized

PDGF-BB, murine recombinant

4489-10 each
EUR 320.4

PDGF-BB, murine recombinant

4489-1000 each
EUR 6434.4

PDGF-BB, murine recombinant

4489-50 each
EUR 874.8

Recombinant Murine PDGF-BB

MEGFP-1601 10ug Ask for price

Human CellExp™ PDGF-BB, human recombinant

7276-10 each Ask for price

PDGF-BB Recombinant Protein

91-179 0.05 mg
EUR 821.4
Description: Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.

PDGF-BB Recombinant Protein

11-380 0.05 mg
EUR 714.3
Description: PDGFs are mitogenic during early developmental stages, driving the proliferation of undifferentiated mesenchyme and some progenitor populations. During later maturation stages, PDGF signalling has been implicated in tissue remodelling and cellular differentiation, and in inductive events involved in patterning and morphogenesis. In addition to driving mesenchymal proliferation, PDGFs have been shown to direct the migration, differentiation and function of a variety of specialised mesenchymal and migratory cell types, both during development and in the adult animal. Other growth factors in this family include vascular endothelial growth factors B and C (VEGF-B, VEGF-C)which are active in angiogenesis and endothelial cell growth, and placenta growth factor (PlGF) which is also active in angiogenesis. PDGF plays a role in embryonic development, cell proliferation, cell migration, and angiogenesis. PDGF is a required element in cellular division for fibroblast, a type of connective tissue cell. PDGF is also known to maintain proliferation of oligodendrocyte progenitor cells. Platelet-derived growth factor subunit B is also known as PDGFB, FLJ12858, PDGF2, SIS, SSV, c-sis, is a member of the platelet-derived growth factor family. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.

PDGF-BB Recombinant Protein

40-458-0002mg 0.002 mg
EUR 311.1
Description: PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant murine PDGF-BB is a 24.4 kDa disulfide-linked homodimer of two B chains (218 total amino acids).

PDGF-BB Recombinant Protein

40-458-001mg 0.01 mg
EUR 437.1
Description: PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant murine PDGF-BB is a 24.4 kDa disulfide-linked homodimer of two B chains (218 total amino acids).

PDGF-BB Recombinant Protein

40-607 0.01 mg
EUR 481.2
Description: PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet a-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-a and PDGFR-β. PDGFR-a is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-BB is a 24.3 kDa disulfide-linked homodimer of two B chains (218 total amino acids). .

PDGF-BB Recombinant Protein

40-158-0002mg 0.002 mg
EUR 311.1
Description: PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-BB is a 24.3 kDa disulfide-linked homodimer of two B chains (218 total amino acids).

PDGF-BB Recombinant Protein

40-158-001mg 0.01 mg
EUR 437.1
Description: PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-BB is a 24.3 kDa disulfide-linked homodimer of two B chains (218 total amino acids).

Recombinant Human Platelet-Derived Growth Factor BB/PDGF-BB

AP74931 1mg
EUR 3209

Recombinant Human Platelet-Derived Growth Factor BB/PDGF-BB

C199-10ug 10ug
EUR 242.4
Description: Lyophilized from a 0.2 μm filtered solution of 4mM HCl.

Recombinant Human Platelet-Derived Growth Factor BB/PDGF-BB

C199-1mg 1mg
EUR 2739.6
Description: Lyophilized from a 0.2 μm filtered solution of 4mM HCl.

Recombinant Human Platelet-Derived Growth Factor BB/PDGF-BB

C199-500ug 500ug
EUR 1935.6
Description: Lyophilized from a 0.2 μm filtered solution of 4mM HCl.

Recombinant Human Platelet-Derived Growth Factor BB/PDGF-BB

C199-50ug 50ug
EUR 595.2
Description: Lyophilized from a 0.2 μm filtered solution of 4mM HCl.

Recombinant Human PDGF-BB Protein (His Tag)(Active)

PKSH030442-1mg 1mg
EUR 4715
Description: Human

Recombinant Human PDGF-BB Protein (His Tag)(Active)

PKSH030442-50ug 50ug
EUR 805
Description: Human

Recombinant Human Platelet Derived Growth Factor-BB (rHu PDGF-BB)

AK8274-0100 100µg
EUR 1740

Recombinant Human Platelet Derived Growth Factor-BB (rHu PDGF-BB)

AK8274-1000 1mg
EUR 4500

Mouse PDGF-BB Recombinant Protein

M10-125 10 µg
EUR 196.35
Description: PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant murine PDGF-BB is a 24.4 kDa disulfide-linked homodimer of two B chains (218 total amino acids).

Mouse PDGF-BB Recombinant Protein

M10-125S 2 µg
EUR 92.4
Description: PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant murine PDGF-BB is a 24.4 kDa disulfide-linked homodimer of two B chains (218 total amino acids).

Recombinant Murine PDGF-BB Protein

PROTP31240-1 10ug
EUR 380.4
Description: PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant murine PDGF-BB is a 24.4 kDa disulfide-linked homodimer of two B chains (218 total amino acids).

PDGF-BB, murine recombinant protein

P1048-.01 10 µg
EUR 302
Description: PDGF-BB, platelet-derived growth factor, expressed in E.Coli.

PDGF-BB, murine recombinant protein

P1048-.05 50 µg
EUR 1052.4
Description: The platelet-derived growth factor BB (PDGF-BB) is a member of the PDGF family and is a disulfide-linked homodimer. PDGF family consists of proteins PDGF-A, -B that form three disulfide-linked homodimers (PDGF-AA, -BB and -AB).

PDGF-BB, murine recombinant protein

P1048-1 1 mg
EUR 7826.4
Description: The platelet-derived growth factor BB (PDGF-BB) is a member of the PDGF family and is a disulfide-linked homodimer. PDGF family consists of proteins PDGF-A, -B that form three disulfide-linked homodimers (PDGF-AA, -BB and -AB).

OPSD00017-2UG - Recombinant PDGF-BB

OPSD00017-2UG 2ug
EUR 108

OPSD00144-2UG - Recombinant PDGF-BB

OPSD00144-2UG 2ug
EUR 108

PDGF-BB Platelet-Derived Growth Factor BB Human Recombinant Protein

PROTP01127-2 Regular: 10ug
EUR 380.4
Description: Platelet-Derived Growth Factor BB Human Recombinant is a homodimeric, non-glycosylated, polypeptide chain containing 2x109 amino acids (218 amino acids in total) and having a molecular mass of 24.3 kDa. PDGF-BB is purified by proprietary chromatographic techniques.

Human PDGF-BB Recombinant Protein Tag Free Lyophilized

IHUPDGFBBRTFLY50UG each
EUR 851
Description: Human PDGF-BB Recombinant Protein Tag Free Lyophilized

Genorise® Recombinant Rat PDGF-BB

GR104260 5 µg
EUR 285

Recombinant Platelet Derived Growth Factor BB (PDGF BB)

RPU50975-100ug 100ug
EUR 443.3

Recombinant Platelet Derived Growth Factor BB (PDGF BB)

RPU50975-1mg 1mg
EUR 1965.6

Recombinant Platelet Derived Growth Factor BB (PDGF BB)

RPU50975-50ug 50ug
EUR 356.4

Recombinant Platelet Derived Growth Factor BB (PDGF BB)

RPU43334-100ug 100ug
EUR 544.5

Recombinant Platelet Derived Growth Factor BB (PDGF BB)

RPU43334-1mg 1mg
EUR 2412.8

Recombinant Platelet Derived Growth Factor BB (PDGF BB)

RPU43334-50ug 50ug
EUR 437.8

Recombinant Platelet Derived Growth Factor BB (PDGF BB)

RPU43335-100ug 100ug
EUR 468.6

Recombinant Platelet Derived Growth Factor BB (PDGF BB)

RPU43335-1mg 1mg
EUR 2074.8

Recombinant Platelet Derived Growth Factor BB (PDGF BB)

RPU43335-50ug 50ug
EUR 376.2

Recombinant Platelet Derived Growth Factor BB (PDGF BB)

RPA633Hu01 10ug
EUR 144

Recombinant Platelet Derived Growth Factor BB (PDGF BB)

RPA633Mu01 10ug
EUR 177

Recombinant Platelet Derived Growth Factor BB (PDGF BB)

RPA633Ra01 10ug
EUR 152

Genorise® Recombinant Sheep PDGF-BB

GR104257 5 µg
EUR 285

Genorise® Recombinant Mouse PDGF-BB

GR104259 5 µg
EUR 285

Platelet-Derived Growth Factor BB (PDGF BB), (Recombinant)

22060762-1 10 µg
EUR 433.84

Genorise® Recombinant Equine PDGF-BB

GR104254 5 µg
EUR 285

Genorise® Recombinant Canine PDGF-BB

GR104255 5 µg
EUR 285

Genorise® Recombinant Bovine PDGF-BB

GR104256 5 µg
EUR 285

Genorise® Recombinant Rabbit PDGF-BB

GR104261 5 µg
EUR 285

Genorise® Recombinant Monkey PDGF-BB

GR175014 5 mg
EUR 285

Genorise® Recombinant Donkey PDGF-BB

GR176014 5 mg
EUR 285

PDGF-BB Platelet Derived Growth Factor-BB Human Recombinant Protein, HEK

PROTP01127-3 Regular: 10ug
EUR 380.4
Description: PDGF-BB Human Recombinant produced in HEK cells is a glycosylated homodimer, having a molecular weight of 25kDa due to glycosylation.;The PDGF-BB is purified by proprietary chromatographic techniques.

Genorise® Recombinant Porcine PDGF-BB

GR104253 5 µg
EUR 285

Genorise® Recombinant Chicken PDGF-BB

GR104262 5 µg
EUR 285

Active Recombinant Mouse PDGF-BB Protein

RP01745 20μg
EUR 52

Mouse PDGF-BB Recombinant Protein Lyophilized

IMSPDGFBBRLY2UG each
EUR 341
Description: Mouse PDGF-BB Recombinant Protein Lyophilized

Human PDGF-BB (12.42 kD) Recombinant Protein Tag Free Lyophilized

IHUPDGFBB1242KDRTFLY50UG each
EUR 988
Description: Human PDGF-BB (12.42 kD) Recombinant Protein Tag Free Lyophilized

Recombinant Mouse PDGF-BB Protein (His Tag)

PKSM041293-10ug 10ug
EUR 129
Description: Mouse

Recombinant Mouse PDGF-BB Protein (His Tag)

PKSM041293-50ug 50ug
EUR 375
Description: Mouse

Genorise® Recombinant Guinea Pig PDGF-BB

GR177014 5 mg
EUR 285

Recombinant Human PDGF-AA

HEGFP-0508 10ug Ask for price

Genorise® Recombinant feline PDGF-BB protein

GR186010 5 mg
EUR 285

PDGF-AA, human recombinant

4482-10 each
EUR 398.4

PDGF-AA, human recombinant

4482-1000 each
EUR 8346

PDGF-AA, human recombinant

4482-50 each
EUR 1123.2

PDGF-AB, human recombinant

4485-10 each
EUR 398.4

PDGF-AB, human recombinant

4485-1000 each
EUR 8346

PDGF-AB, human recombinant

4485-50 each
EUR 1123.2

PDGF-CC, human recombinant

7183-10 each
EUR 248.4

PDGF-CC, human recombinant

7183-50 each
EUR 810

 

 

Recombinant Human PDGF-BB Protein

 

Description: PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells.

The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development.

Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-BB is a 24.3 kDa disulfide-linked homodimer of two B chains (218 total amino acids).

Moreover, PDGFR-β siRNA-PEI-PLGA-PEG NP decreased PDGFR-β mRNA expression by 50% and protein expression by 43% in VK2/E6E7 cells 48 hr publish remedy.

Remedy of cells with PDGFR-β siRNA-PEI-PLGA-PEG NP considerably decreased the intracellular C. trachomatis and extracellular launch of C. trachomatis by roughly 65% and 67%, respectively, in vitro via augmenting autophagic degradation pathways and lowering bacterial binding concurrently.

Deregulation of VEGFR-2 and PDGFR Expression and Microvascular Density in a Triple-Damaging Mannequin of Canine Malignant Mammary Tumors with Lymph Node or Lung Metastasis.

Canine mammary tumors (CMT) symbolize the commonest most cancers in noncastrated feminine canines. Apparently, triple-negative tumors are the commonest molecular subtype in feminine canines. On this examine, we proposed to judge the expression of vascular endothelial development issue receptor 2 (VEGFR-2), Platelet-derived development issue receptor (PDGFR), and microvascular density (MVD) in a bunch of metastatic and nonmetastatic triple-negative CMT and evaluate the expression primarily based on scientific parameters.
Twenty-six feminine canines with triple-negative mammary tumors had been divided into three teams: nonmetastatic tumors (NMT) (n = 11), tumors with lymph node metastasis (LNM) (n = 10), and tumors with lung metastasis (LM) (n = 5).

Recombinant Human Platelet-Derived Growth Factor BB/PDGF-BB

We noticed elevated VEGFR-2 expression in LNM in contrast with NMT and a constructive correlation between tumor grade and VEGFR-2 expression. A constructive correlation was famous between VEGFR-2 and PDGFR expression.
Relating to microvascular density (MVD), we recognized the next variety of vessels in main tumors with lymph node metastasis and lung metastasis in contrast with tumors with no metastasis. The first tumors with lung metastasis exhibited an elevated MVD in contrast with carcinoma with lymph node metastasis.
Total, our outcomes counsel a deregulation of VEGFR-2 and PDGFR and excessive MVD in metastatic tumors, indicating a task for angiogenesis in tumor development.

 

 

 

PDGFC Antibody

1-CSB-PA243546
  • Ask for price
  • Ask for price
  • 100ug
  • 50ug
Description: A polyclonal antibody against PDGFC. Recognizes PDGFC from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC-p:1:50-300, ELISA:1:10000-20000

PDGFC Antibody

1-CSB-PA108491
  • Ask for price
  • Ask for price
  • 100ul
  • 50ul
Description: A polyclonal antibody against PDGFC. Recognizes PDGFC from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:50-1:200

PDGFC Antibody

1-CSB-PA146607
  • Ask for price
  • Ask for price
  • 100ul
  • 50ul
Description: A polyclonal antibody against PDGFC. Recognizes PDGFC from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:50-1:200

OACD06377-1ML - PDGFC Antibody

OACD06377-1ML 1ml
EUR 649

OACD06377-100UL - PDGFC Antibody

OACD06377-100UL 100ul
EUR 199

PDGFC Polyclonal Antibody

E915174 100ul
EUR 225
Description: Available in various conjugation types.

PDGFC Conjugated Antibody

C37811 100ul
EUR 476.4

PDGFC Polyclonal Antibody

E-AB-13501-120uL 120uL
EUR 240
Description: Unconjugated

PDGFC Polyclonal Antibody

E-AB-13501-200uL 200uL
EUR 399
Description: Unconjugated

PDGFC Polyclonal Antibody

E-AB-13501-20uL 20uL
EUR 73
Description: Unconjugated

PDGFC Polyclonal Antibody

E-AB-13501-60uL 60uL
EUR 143
Description: Unconjugated

PDGFC Polyclonal Antibody

E-AB-16697-120uL 120uL
EUR 240
Description: Unconjugated

PDGFC Polyclonal Antibody

E-AB-16697-200uL 200uL
EUR 399
Description: Unconjugated

PDGFC Polyclonal Antibody

E-AB-16697-20uL 20uL
EUR 73
Description: Unconjugated

PDGFC Polyclonal Antibody

E-AB-16697-60uL 60uL
EUR 143
Description: Unconjugated

PDGFC Polyclonal Antibody

E-AB-91057-120uL 120uL
EUR 320
Description: Unconjugated

PDGFC Polyclonal Antibody

E-AB-91057-200uL 200uL
EUR 530
Description: Unconjugated

PDGFC Polyclonal Antibody

E-AB-91057-60uL 60uL
EUR 200
Description: Unconjugated

PDGFC Polyclonal Antibody

E-AB-91057-each each Ask for price
Description: Unconjugated

PDGFC (230-345) goat polyclonal antibody

GT15151-100 100 µg Ask for price

PDGFC Rabbit Polyclonal Antibody

E300763 100ug/200ul
EUR 295
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

PDGFC Rabbit Polyclonal Antibody

E10G05150 100 μl
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

PDGFC Rabbit Polyclonal Antibody

E10G12037 100 μl
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

ARP87717_P050-25UL - PDGFC Antibody - middle region

ARP87717_P050-25UL 25ul
EUR 99

ARP87717_P050 - PDGFC Antibody - middle region (ARP87717_P050)

ARP87717_P050 100ul
EUR 389

Platelet Derived Growth Factor C (PDGFC) Antibody

20-abx326887
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  • 100 ug
  • 50 ug

Platelet Derived Growth Factor C (PDGFC) Antibody

20-abx131438
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Platelet Derived Growth Factor C (PDGFC) Antibody

20-abx174096
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  • 1 mg
  • 200 ug

Platelet Derived Growth Factor C (PDGFC) Antibody

20-abx174097
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  • 1 mg
  • 200 ug

Platelet Derived Growth Factor C (PDGFC) Antibody

20-abx178044
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  • 1 mg
  • 200 ug

Platelet Derived Growth Factor C (PDGFC) Antibody

20-abx241696
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  • 100 ul
  • 50 ul

Platelet Derived Growth Factor C (PDGFC) Antibody

20-abx241697
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  • 100 ul
  • 50 ul

Platelet Derived Growth Factor C (PDGFC) Antibody

20-abx103486
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Platelet Derived Growth Factor C (PDGFC) Antibody

20-abx103487
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Platelet Derived Growth Factor C (PDGFC) Antibody

abx131438-05mg 0.5 mg
EUR 275

Platelet Derived Growth Factor C (PDGFC) Antibody

abx103486-100g 100 µg
EUR 750

Platelet Derived Growth Factor C (PDGFC) Antibody

abx103486-20g 20 µg
EUR 275

Platelet Derived Growth Factor C (PDGFC) Antibody

abx103486-50g 50 µg
EUR 337.5

Platelet Derived Growth Factor C (PDGFC) Antibody

abx103487-100g 100 µg
EUR 775

Platelet Derived Growth Factor C (PDGFC) Antibody

abx103487-20g 20 µg
EUR 275

Platelet Derived Growth Factor C (PDGFC) Antibody

abx103487-50g 50 µg
EUR 350

Platelet Derived Growth Factor C (PDGFC) Antibody

abx241696-96tests 96 tests
EUR 250

Platelet Derived Growth Factor C (PDGFC) Antibody

abx241697-96tests 96 tests
EUR 250

Platelet Derived Growth Factor C (PDGFC) Antibody

abx174096-100l 100 µl
EUR 787.5

Platelet Derived Growth Factor C (PDGFC) Antibody

abx174096-1ml 1 ml Ask for price

Platelet Derived Growth Factor C (PDGFC) Antibody

abx174096-200l 200 µl Ask for price

Platelet Derived Growth Factor C (PDGFC) Antibody

abx375327-96tests 96 tests
EUR 337.5

Platelet Derived Growth Factor C (PDGFC) Antibody

abx326887-100g 100 µg
EUR 250

Platelet Derived Growth Factor C (PDGFC) Antibody

abx326887-50g 50 µg
EUR 187.5

PDGFC Antibody / Platelet-derived growth factor C

RQ6785 100ug
EUR 356.15
Description: Platelet-derived growth factor C, also known as PDGF-C, is a 345-amino acid protein that in humans is encoded by the PDGFC gene. The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines. This gene product appears to form only homodimers. It differs from the platelet-derived growth factor alpha and beta polypeptides in having an unusual N-terminal domain, the CUB domain. Alternatively spliced transcript variants have been found for this gene.

ARP61794_P050-25UL - Pdgfc Antibody - N-terminal region

ARP61794_P050-25UL 25ul
EUR 99

ARP61795_P050-25UL - PDGFC Antibody - C-terminal region

ARP61795_P050-25UL 25ul
EUR 99

ARP81876_P050-25UL - PDGFC Antibody - N-terminal region

ARP81876_P050-25UL 25ul
EUR 99

ARP61794_P050 - Pdgfc Antibody - N-terminal region (ARP61794_P050)

ARP61794_P050 100ul
EUR 389

ARP61795_P050 - PDGFC Antibody - C-terminal region (ARP61795_P050)

ARP61795_P050 100ul
EUR 389

ARP81876_P050 - PDGFC Antibody - N-terminal region (ARP81876_P050)

ARP81876_P050 100ul
EUR 389

Platelet Derived Growth Factor C (PDGFC) Polyclonal Antibody

CAU23738-100ul 100ul
EUR 241.9

Platelet Derived Growth Factor C (PDGFC) Polyclonal Antibody

CAU23738-200ul 200ul
EUR 302.4

Platelet Derived Growth Factor C (PDGFC) Polyclonal Antibody

CAU23739-100ul 100ul
EUR 241.9

Platelet Derived Growth Factor C (PDGFC) Polyclonal Antibody

CAU23739-200ul 200ul
EUR 302.4

Platelet Derived Growth Factor C (PDGFC) Polyclonal Antibody

CAU23740-100ul 100ul
EUR 235.2

Platelet Derived Growth Factor C (PDGFC) Polyclonal Antibody

CAU23740-200ul 200ul
EUR 294

Platelet-derived growth factor C (PDGFC) polyclonal antibody

ABP-PAB-10942 100 ug Ask for price

PDGFC siRNA

20-abx928112
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  • 15 nmol
  • 30 nmol

PDGFC siRNA

20-abx928113
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  • 15 nmol
  • 30 nmol

PDGFC siRNA

20-abx903903
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  • 15 nmol
  • 30 nmol

Polyclonal Antibody to Platelet Derived Growth Factor C (PDGFC)

PAC920Hu01 100ul
EUR 245

Polyclonal Antibody to Platelet Derived Growth Factor C (PDGFC)

PAC920Mu01 100ul
EUR 252

Polyclonal Antibody to Platelet Derived Growth Factor C (PDGFC)

PAC920Mu02 100ul
EUR 252

Platelet Derived Growth Factor C (PDGFC) Polyclonal Antibody (Human)

4-PAC920Hu01
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Platelet Derived Growth Factor C (PDGFC)

Platelet Derived Growth Factor C (PDGFC) Polyclonal Antibody (Mouse)

4-PAC920Mu01
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Platelet Derived Growth Factor C (PDGFC)

Platelet Derived Growth Factor C (PDGFC) Polyclonal Antibody (Mouse)

4-PAC920Mu02
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Platelet Derived Growth Factor C (PDGFC)

Platelet Derived Growth Factor C (PDGFC) Polyclonal Antibody (Human), PE

4-PAC920Hu01-PE
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Platelet Derived Growth Factor C (PDGFC). This antibody is labeled with PE.

Platelet Derived Growth Factor C (PDGFC) Polyclonal Antibody (Mouse), PE

4-PAC920Mu01-PE
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Platelet Derived Growth Factor C (PDGFC). This antibody is labeled with PE.

Platelet Derived Growth Factor C (PDGFC) Polyclonal Antibody (Mouse), PE

4-PAC920Mu02-PE
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Platelet Derived Growth Factor C (PDGFC). This antibody is labeled with PE.

Platelet Derived Growth Factor C (PDGFC) Polyclonal Antibody (Human), APC

4-PAC920Hu01-APC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Platelet Derived Growth Factor C (PDGFC). This antibody is labeled with APC.

Platelet Derived Growth Factor C (PDGFC) Polyclonal Antibody (Human), Cy3

4-PAC920Hu01-Cy3
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Platelet Derived Growth Factor C (PDGFC). This antibody is labeled with Cy3.

Platelet Derived Growth Factor C (PDGFC) Polyclonal Antibody (Human), FITC

4-PAC920Hu01-FITC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Platelet Derived Growth Factor C (PDGFC). This antibody is labeled with FITC.

Platelet Derived Growth Factor C (PDGFC) Polyclonal Antibody (Human), HRP

4-PAC920Hu01-HRP
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Platelet Derived Growth Factor C (PDGFC). This antibody is labeled with HRP.

Platelet Derived Growth Factor C (PDGFC) Polyclonal Antibody (Mouse), APC

4-PAC920Mu01-APC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Platelet Derived Growth Factor C (PDGFC). This antibody is labeled with APC.

Platelet Derived Growth Factor C (PDGFC) Polyclonal Antibody (Mouse), Cy3

4-PAC920Mu01-Cy3
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Platelet Derived Growth Factor C (PDGFC). This antibody is labeled with Cy3.

Platelet Derived Growth Factor C (PDGFC) Polyclonal Antibody (Mouse), FITC

4-PAC920Mu01-FITC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Platelet Derived Growth Factor C (PDGFC). This antibody is labeled with FITC.

Platelet Derived Growth Factor C (PDGFC) Polyclonal Antibody (Mouse), HRP

4-PAC920Mu01-HRP
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Platelet Derived Growth Factor C (PDGFC). This antibody is labeled with HRP.

Platelet Derived Growth Factor C (PDGFC) Polyclonal Antibody (Mouse), APC

4-PAC920Mu02-APC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Platelet Derived Growth Factor C (PDGFC). This antibody is labeled with APC.