Vascular endothelial growth factor A

Vascular endothelial growth factor A

Member of the PDGF/VEGF growth factor family

Dispersion Element For Tissue Homogenizer S12N 7S 431 0111 Vwr

Lab Reagents

Human IgG antibody Laboratories manufactures the dispersion element for tissue homogenizer s12n 7s 431 0111 vwr reagents distributed by Genprice. The Dispersion Element For Tissue Homogenizer S12N 7S 431 0111 Vwr reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact Tissue homogenizer. Other Dispersion products are available in stock. Specificity: Dispersion Category: Element Group: For Tissue

For Tissue information

Mouse Anti-Soybean 7s globulin monoclonal antibody, clone 7SD

CABT-L4256D-1mg 1 mg
EUR 1575.6

A-431 Cell Slide

17-002 1 pack
EUR 216.6
Description: A-431 (epidermis; epidermoid carcinoma)

mmu-miR-431 Primers

MPM00474 150 ul / 10 uM
EUR 145.2

rno-miR-431 Primers

MP-r00166 150 ul / 10 uM
EUR 211.2

hsa-miR-431 Primers

MPH01675 150 ul / 10 uM
EUR 145.2

ELISA kit for Human cAMP-responsive element modulator

EK3696 96 tests
EUR 804
Description: Enzyme-linked immunosorbent assay kit for quantification of Human cAMP-responsive element modulator in samples from serum, plasma, tissue homogenates and other biological fluids.

Holder for Plasmid Midi, Maxi and Maxi plus, Ion Exchange column

FAPDE-holder-for-ion-exchange 1 prep
EUR 189.6

SARS-CoV-2 (COVID-19) S RBD Recombinant Protein

10-431 0.1 mg
EUR 714.3
Description: Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

DNAM-1 / CD226 Recombinant Protein

11-431 0.1 mg
EUR 714.3
Description: DNAX accessory molecule 1 (DNAM-1), a single-pass type I membrane protein, is also known as CD226 antigen and platelet and T cell activation antigen 1 (PTA1), which contains 2 Ig-like C2-type (immunoglobulin-like) domains. DNAM-1 is a ~65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2.

CD274 [B7-H1/PD-L1] Recombinant Protein

90-431 100 ug
EUR 651.3
Description: Programmed death ligand 1 (PD-L1, B7-H1 or CD274) is a member of the growing B7 family of immune proteins that provide signals for both stimulating and inhibiting T cell activation. CD274 has been identified as one of two ligands for programmed death 1 (PD-1), a member of the CD28 family of immunoreceptors. CD274 is widely expressed in several organs such as heart, skeletal muscle, placenta and lung, and in lower amounts in thymus, spleen, kidney and liver. CD274 expression is upregulated in a small fraction of activated T and B cells and a much larger fraction of activated monocytes. CD274 expression is also induced in dendritic cells and keratinocytes after IFN-gamma stimulation. CD274 expression is also upregulated in a variety of tumor cell lines. Interaction of CD274 with PD-1 results in inhibition of TCR mediated proliferation and cytokine production, suggesting an inhibitory role in regulating immune responses. The CD274 - PD-1 pathway is involved in the negative regulation of some immune responses and may play an important role in the regulation of peripheral tolerance.

IFN alpha Recombinant Protein

91-431 0.05 mg
EUR 556.8
Description: Interferon alpha/ beta Receptor 2 (IFN- alpha/ beta R2) is a single-pass type I membrane protein which belongs to the type II cytokine receptor family. It complexes with IFN- alpha/ beta R1 to form the signaling receptor complex for the family of alpha and beta IFN subtypes. By alternative splicing, IFN- alpha/ beta R2 can exist as a secreted soluble protein or as a type I membrane protein. IFN- alpha/ beta R2 is the principal ligand binding subunit of the receptor. Ligand binding is stabilized by the subsequent association with IFN- alpha/ beta R1, resulting in the formation of a signaling ternary receptor complex. IFNAR2 was detected in most lymphocytes, monocytes, and granulocytes, although IFNAR2 expression was higher in the monocytes and granulocytes than in the lymphocytes. Among the lymphocyte subsets, IFNAR2 showed high expression in natural killer (NK) cells and low expression in T lymphocytes. Isoform 1 and isoform 3 of IFNAR2 are directly involved in signal transduction due to their interaction with the TYR kinase, JAK1. Isoform 1 also interacts with the transcriptional factors, STAT1 and STAT2. Both forms are potent inhibitors of type I IFN activity.

IL-22 Binding Protein Recombinant Protein

92-431 0.05 mg
EUR 651.3
Description: Interleukin-22 Receptor Subunit alpha-2 (IL22RA2) belongs to the type II cytokine receptor family. IL22RA2 is a secreted protein and contains three fibronectin type-III domains. IL22RA2 is widely expressed in many tissues. IL22RA2 functions as an IL22 antagonist and may be important in the regulation of inflammatory response. Three alternatively spliced transcript variants encoding distinct isoforms have been described.

IL13RA1 Recombinant Protein

96-431 0.2 mg
EUR 556.8
Description: Interleukin 13 receptor, alpha 1 is also known as IL13RA1, NR4 and CD213A1 (cluster of differentiation 213A1), The IL13 Rα1 cDNA encodes a 427 amino acid (aa) residue precursor protein with a putative 21 aa residue signal peptide, a 324 aa residue extracellular domain, a 23 aa residue transmembrane region and a 59 aa residue cytoplasmic tail. Human and mouseIL13Rα1 share 76% aa sequence identity. IL13RA1 is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.

RhoA G17A Agarose Beads (Active Rho-GEF)

STA-431 400 µg
EUR 838.8
Description: RhoA G15A Agarose Beads selectively pull down the active form of RhoA GEF. Beads are colored to allow for a visual check. 400 µg.

Recombinant (E.Coli) Beta Lactamase

RP-431 1 mg
EUR 343.2

Lipopolysaccharides (LPS) (Escherichia coli 0111:B4) vaccine adjuvant, ultrapure, TLR4 tested

AV-7016-1 1 mg
EUR 196.8

Lipopolysaccharides (LPS) (Escherichia coli 0111:B4) vaccine adjuvant, ultrapure, TLR4 tested

AV-7016-5 5 mg
EUR 416.4